Psilocybin,
the psychedelic compound in magic mushrooms, may be an effective treatment for
depression. A pilot study of psilocybin’s use in cases of treatment-resistant
depression showed it was safe and effective. Of 12 patients given the drug, all
showed some decrease in symptoms of depression for at least three weeks. Seven
continued to show a positive response at three months. Five remained in
remission beyond the three months. Many patients described a profound
experience. Magic mushrooms have been used since ancient times, both for
recreation and for religious rites. Psilocybin acts on the serotonin system, suggesting
it could be developed for treating depression. WHO estimated that some 350
million people are affected by depression.
Monday, 29 August 2016
Dreams help you make memories
Rapid
eye movement (REM) sleep – the phase where dreams appear – plays a key role in
memory formation, a new study involving mice has found. We already knew that
newly acquired information is stored into different types of memories, spatial
or emotional, before being consolidated or integrated. How the brain performs
this process has remained unclear. When mice were in REM sleep, the researchers
used light pulses to turn off their memory-associated neurons to determine if
it affects their memory consolidation. The next day, the rodents did not
succeed in a spatial memory task learned the previous day. Silencing the same neurons
for similar durations outside REM episodes had no effect on memory. This indicates
that neuronal activity specifically during REM sleep is required for normal
memory consolidation.
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